STARmed Endoscopic Ultrasound
(EUS)-guided Ablation

An effective, minimally invasive alternative for pancreatic and extra-pancreatic tumors

Local control of advanced pancreatic tumors

With the evolution of endoscopic RFA therapies, STARmed introduced EUSRA^TM – an advanced technique of Endoscopic Ultrasound (EUS)-Guided Radiofrequency Ablation. This innovative approach utilizes EUS to precisely target and ablate locally advanced lesions, providing a safe and feasible alternative for managing borderline resectable and unresectable pancreatic cancers, neuroendocrine tumors, cystic neoplasms, and lesions in other systems.

<5%¹

5-year survival rate for pancreatic cancer, but varies based on the stage of cancer at diagnosis.

~95%²

of pancreatic cancers are adenocarcinomas, with most patients diagnosed at stage IV.

3%-14%³

Mortality rates of surgical resection of benign tumors like neuroendocrine tumors (NETs).

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Real-time imaging

The real-time EUS guidance with Doppler enhances visualization of the targeted anatomical structures. This ensures minimal passage through normal pancreatic tissue and avoids critical structures like major vessels and the pancreatic duct.

Internal cooling system

During an ablation, the EUSRA^TM electrode is continuously cooled and perfused internally with circulating chilled saline solution delivered by the VIVA pump. This prevents the charring of the electrode surface, improving the treatment’s accuracy and efficiency.⁴

Diverse applications

Physicians around the world have been exploring diverse applications of the EUSRA^TM electrode. Beyond pancreatic treatments, it has also shown efficacy in treating extra-pancreatic tumors, such as hepatocellular carcinoma (HCC), adrenal tumors, the celiac plexus, and gastrointestinal stromal tumor.

PRODUCT INDICATIONS

The EUSRA RF Electrode is indicated for coagulation and ablation of soft tissue when used in conjunction with a compatible radiofrequency generator.

Reference

Song, T. J., Seo, D. W., Lakhtakia, S., Reddy, N., Oh, D. W., Park, D. H., Lee, S. S., Lee, S. K., & Kim, M.-H. (2016). Initial experience of eus-guided radiofrequency ablation of unresectable pancreatic cancer. Gastrointestinal Endoscopy, 83(2), 440–443. https://doi.org/10.1016/j.gie.2015.08.048
What is pancreatic cancer?: Types of pancreatic cancer. Types of Pancreatic Cancer | American Cancer Society. (n.d.). https://www.cancer.org/cancer/types/pancreatic-cancer/about/what-is-pancreatic-cancer.html
Law, R., & Levy, M. J. (2021). Follow-up after EUS-guided radiofrequency ablation for pancreatic lesions: With more answers, come more questions. Endoscopy International Open, 09(08). https://doi.org/10.1055/a-1393-5780
Lakhtakia, S., Ramchandani, M., Galasso, D., Gupta, R., Venugopal, S., Kalpala, R., & Reddy, D. N. (2016). EUS-guided radiofrequency ablation for management of pancreatic insulinoma by using a novel needle electrode (with videos). Gastrointestinal Endoscopy, 83(1), 234–239. https://doi.org/10.1016/j.gie.2015.08.085