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Pancreatic Tumors

EUS-Guided RFA

Minimally Invasive Management for Pancreatic and Extra-Pancreatic Tumors

Pancreatic cancer remains one of the most challenging malignancies to treat. For these patients, EUS RFA provides a safe and minimally invasive alternative that can enhance local control and expand therapeutic options.

<5%

5-year survival rate for advanced pancreatic cancer¹

~95%

Pancreatic cancers are diagnosed at stage IV²

3–14%

Surgical mortality rates for NET (neuroendocrine tumors) resections³

How does Endoscopic Ultrasound-Guided RFA work?

EUSRA™ delivers targeted, controlled heat to pancreatic and peri-pancreatic lesions under direct endoscopic ultrasound guidance. The electrode is cooled internally to maintain safe, consistent ablation zones while minimizing tissue damage.

  • Target: EUS identifies the lesion.
  • Ablate: RF energy applied with real-time monitoring.
  • Control: Coagulative necrosis achieved, sparing adjacent structures

Applications Beyond the Pancreas

While widely studied in pancreatic adenocarcinoma and NETs, EUSRA™ has been used in a variety of extra-pancreatic tumors and pain syndromes:

Other Applications

  • Pancreatic adenocarcinoma
  • Pancreatic cystic lesions
  • Neuroendocrine tumors (NETs)
  • Hepatocellular carcinoma (HCC)
  • Adrenal tumors
  • Celiac plexus ablation
  • Gastrointestinal stromal tumors
Explore Clinical Articles
Image illustrates how the EUS RFA device is used inside the body, showing the probe inserted through the mouth and positioned near the pancreas to target a tumor for ablation.

Technology that Supports Confident Ablation

Real-Time Imaging

Doppler-enhanced EUS visualization reduces the risk of injuring vessels or ducts.

Internal Cooling

Circulating saline prevents charring, improving consistency and safety.

Flexible Portfolio

Multiple electrode sizes for diverse lesions.

  1. Song, T. J., Seo, D. W., Lakhtakia, S., Reddy, N., Oh, D. W., Park, D. H., Lee, S. S., Lee, S. K., & Kim, M.-H. (2016). Initial experience of eus-guided radiofrequency ablation of unresectable pancreatic cancer. Gastrointestinal Endoscopy, 83(2), 440–443. https://doi.org/10.1016/j.gie.2015.08.048
  2. What is pancreatic cancer?: Types of pancreatic cancer. Types of Pancreatic Cancer | American Cancer Society. (n.d.). https://www.cancer.org/cancer/types/pancreatic-cancer/about/what-is-pancreatic-cancer.html
  3. Law, R., & Levy, M. J. (2021). Follow-up after EUS-guided radiofrequency ablation for pancreatic lesions: With more answers, come more questions. Endoscopy International Open, 09(08). https://doi.org/10.1055/a-1393-5780
  4. Lakhtakia, S., Ramchandani, M., Galasso, D., Gupta, R., Venugopal, S., Kalpala, R., & Reddy, D. N. (2016). EUS-guided radiofrequency ablation for management of pancreatic insulinoma by using a novel needle electrode (with videos). Gastrointestinal Endoscopy, 83(1), 234–239. https://doi.org/10.1016/j.gie.2015.08.085
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